- Scientists and researchers interested in stability of biopharmaceuticals, such as peptides.
- Learn how to better understand peptide population distributions and agglomeration tendencies Understand how SAXS and SEC-MALS can overcome the limitations of DLS, particularly in studying peptide aggregation and distribution across different populations.
- Partnering for innovation: Learn about the collaboration between Malvern Panalytical and Xenocs and how the combination of our tools and expertise delivers innovative solutions for biophysical characterization
- Biologics Deep Dive: Explore orthogonal techniques for stability assessment of peptide-based therapeutics.
- A closer look at lipid nanoparticles (LNPs): Understand the structure and stability behavior of these complex drug delivery systems.
- Webinar 1: October 23, 2024 - Key tools for understanding drug efficacy and stability
- Webinar 2: November 20, 2024 - Complementary techniques for biophysical characterization of peptides and protein-based drug products
- Webinar 3: December 10, 2024 - Elucidating the internal structure of RNA based therapeutics and vaccines
- Higher-order structural changes and thermal stability
- Particle size distribution, aggregation propensity, polydispersity, and particle concentration
- Absolute molecular weight and molecular size
- Protein structural arrangements, including conformational states and multimer formation
- The structure and composition of lipid nanoparticles (LNPs), which are increasingly favored as drug delivery systems
Complementary techniques for biophysical characterization of peptides and protein-based drug products
Application of Small-Angle X-ray Scattering in pharmaceutical peptide/protein drug development at Novo Nordisk
November 20, 2024 | 15:00 - 16:00 CET | Virtual
About The Event
In early research and development of peptide and new protein- based drug products, the combination of biophysical and structural properties is used to inform rational design of stable pharmaceutical formulation. In this webinar, we will share how Small-Angle X-ray Scattering (SAXS) complemented with other scattering methods allows detailed investigation of protein and peptide behaviour across various sample conditions, and can be used to inform triaging of lead candidates or to optimise formulation conditions. Sign up and learn how Novo Nordisk is combining Dynamic Light Scattering (DLS) with Small-Angle X-ray Scattering (SAXS) and Size-Exclusion Chromatography Multi-Angle Light Scattering (SEC-MALS) to better understand peptide population distribution and study agglomeration.
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About the series: Focus on Biopharmaceuticals
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About the Malvern Panalytical & Xenocs collaboration
Malvern Panalytical brings decades of expertise in the characterization of (bio)pharmaceuticals, offering a suite of advanced analytical methods and instrumentation. Our technologies provide critical insights into:
As a leader in Small-Angle X-ray Scattering (SAXS), Xenocs offers state-of-the-art solutions for the structural characterization of materials at the nanoscale. By merging advanced academic techniques with industrial applications in drug development, Xenocs' instrumentation provides unmatched insights into:
Join us to explore how these advanced analytical techniques can be combined to drive innovation and ensure the success of your biopharmaceutical development efforts.
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