Delivering a breakthrough level of interaction analysis to facilitate drug discovery
Introducing the patented GCI technique for label-free analysis

About The Event

The accurate and efficient measurement of intermolecular interactions and binding events is a critical element for all manner of basic research and an indispensable component of drug discovery programs. Ligand binding assays can be performed using labeled molecules (radiolabels, fluorescent labels, etc.), but appropriate, non-disruptive labeling and often elaborate washing and purification steps are required. Additionally, the kinetics of interactions are not easily acquired or understood using these methods. Surface plasmon resonance (SPR) changed the game with its ability to monitor and measure interactions in real time using unlabeled species, but challenges remain. Measurements usually require significant time investment because they involve repeated introductions of increasing concentrations of analyte, and they are sensitive to bulk refractive index changes in buffers; these issues limit the utility of SPR in screening programs. Join us for a free workshop on high throughput analysis for binding affinity and kinetics. During the workshop, learn how to accelerate your discovery research from small molecules to biologics, from GCI’s RAPID analysis for determining the binding kinetics of drug candidates to drug targets to orthogonal validation and in-depth biophysical characterization. Gain greater insights through case studies and hands-on time with the GCI and ITC techniques. We are proud to have on display the waveRAPID®, which is the most sensitive optical sensing-based label-free analysis standard.