Analytica Vietnam - Talk on stability and bioavailability in pharmaceutical drugs on 19 April

About The Event

Malvern Panalytical, represented by DKSH Vietnam, will be present at Analytica Vietnam. Look out for a talk by our application specialist, Tamal Mukherjee, who specialises in analytical methodologies for pharmaceutical industries. His talk is on 19th April entitled: Assessing the formulation, stability and bioavailability of nasal sprays and dry powder inhalers with cutting edge laboratory solutions While the advantages of Orally Inhaled and Nasal Drug products for both systemic and locally acting drug delivery are widely understood, the challenge remains to develop products with the required performance. The property of the formulation, the design of the delivery device and the actuation characteristics of the target user group all influence dispersion behaviour in case of OINDP products like nasal sprays, dry powder inhalers. Physical parameters of the drug and excipients like particle size, shape, density, polymorphic form etc. plays a critical role in formulation, stability and bioavailability of the drug Determining the droplet size and its distribution during spray event is challenging as typically an actuation is complete in about a tenth of a second. Further to this, regulatory guidance also demands that particle size of drug in droplet also needs to be determined for a better understanding of how a nasal spray product interacts with the body. Understanding of the polymorphic form of the active ingredient is useful from a stability as well as regulatory perspective. The presentation will discuss about Malvern Panalytical platforms such as Mastersizer 3000, Spraytec, Morphologi 4-ID and Empyrean systems and how they are useful in deformulation and development of inhalation products